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Aclidinium bromide for stable chronic obstructive pulmonary disease

Action plans with brief patient education for exacerbations in chronic obstructive pulmonary disease

Active mind-body movement therapies as an adjunct to or in comparison with pulmonary rehabilitation for people with chronic obstructive pulmonary disease

Acupuncture for chronic asthma

Acupuncture point stimulation for chronic obstructive pulmonary disease

Addition of anti-leukotriene agents to inhaled corticosteroids for adults and adolescents with persistent asthma

Addition of anti-leukotriene agents to inhaled corticosteroids for chronic asthma

Addition of anti-leukotriene agents to inhaled corticosteroids in children with persistent asthma

Addition of intravenous aminophylline to inhaled beta₂-agonists in adults with acute asthma

Addition of intravenous beta₂-agonists to inhaled beta₂-agonists for acute asthma

Addition of long-acting beta-agonists to inhaled corticosteroids for chronic asthma in children

Addition of long-acting beta2-agonists to inhaled corticosteroids versus same dose inhaled corticosteroids for chronic asthma in adults and children

Addition of long-acting beta2-agonists to inhaled steroids as first line therapy for persistent asthma in steroid-naive adults and children

Addition of long-acting beta2-agonists to inhaled steroids versus higher dose inhaled steroids in adults and children with persistent asthma

Addition to inhaled corticosteroids of long-acting beta-agonists versus anti-leukotrienes for chronic asthma

Airway clearance techniques for bronchiectasis

Airway clearance techniques for chronic obstructive pulmonary disease

Alexander technique for chronic asthma

Ambulatory and short-burst oxygen for interstitial lung disease

Ambulatory oxygen for people with chronic obstructive pulmonary disease who are not hypoxaemic at rest

Anti-IL5 therapies for asthma

New

Anti-IL5 therapies for chronic obstructive pulmonary disease

Anti-fibrotic therapies for idiopathic pulmonary fibrosis and other fibrotic interstitial lung diseases

Anti-histamines for prolonged non-specific cough in children

Anti-inflammatory medications for obstructive sleep apnea in children

Anti-interleukin-13 and anti-interleukin-4 agents versus placebo, anti-interleukin-5 or anti-immunoglobulin-E agents, for children and adults with asthma

Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children

Antibiotics for acute and chronic pulmonary infection in children with a neurodisability

Antibiotics for exacerbations of asthma

Antibiotics for exacerbations of chronic obstructive pulmonary disease

Antibiotics for persistent cough or wheeze following acute bronchiolitis in children

Antibiotics for prolonged wet cough in children

Anticholinergic agents for chronic asthma in adults

Anticholinergic bronchodilators versus beta2-sympathomimetic agents for acute exacerbations of chronic obstructive pulmonary disease

Anticholinergic drugs for wheeze in children under the age of two years

Anticholinergic therapy for acute asthma in children

Anticholinergic therapy for bronchiectasis

Anticholinergic therapy for chronic asthma in children over two years of age

Anticholinergics for prolonged non-specific cough in children

Anticoagulation therapy versus placebo for pulmonary hypertension

Antileukotriene agents compared with placebo in children and adults with mild asthma

Asthma education for school staff

Asthma self management education with either regular healthcare professional review or written action plans or both in adults

Azathioprine as an oral corticosteroid sparing agent for asthma

Azoles for allergic bronchopulmonary aspergillosis associated with asthma

Beclometasone for chronic obstructive pulmonary disease

Beclomethasone at different doses for chronic asthma

Beclomethasone for asthma in children: effects on linear growth

Beclomethasone versus budesonide for chronic asthma

Beclomethasone versus placebo for chronic asthma

Beta agonist and steroid in one inhaler as required for adults or children with mild asthma

Beta-agonists for exercise-induced asthma

Biomarkers to guide antibiotic therapy for COPD exacerbations

Breathing exercises for adults with asthma

Breathing exercises for children with asthma

Breathing exercises for chronic obstructive pulmonary disease

Breathing exercises for dysfunctional breathing/hyperventilation syndrome in adults

Breathing exercises for dysfunctional breathing/hyperventilation syndrome in children

Bronchial thermoplasty for moderate or severe persistent asthma in adults

Bronchodilators delivered by nebuliser versus pMDI with spacer or DPI for exacerbations of COPD

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease

Budesonide at different doses for chronic asthma

Budesonide versus placebo for chronic asthma in children and adults

Buteyko Method for people with asthma

Caffeine for asthma

Calcium channel blockers for pulmonary arterial hypertension

Calorie controlled diet for chronic asthma

Carbonic anhydrase inhibitors for hypercapnic ventilatory failure in chronic obstructive pulmonary disease

Cardioselective beta-blockers for chronic obstructive pulmonary disease

Cardioselective beta-blockers for reversible airway disease

Caseworker-assigned discharge plans to prevent hospital readmission for acute exacerbations in children with chronic respiratory illness

Chloroquine as a steroid sparing agent for asthma

Ciclesonide versus other inhaled corticosteroids for chronic asthma in children

Ciclesonide versus other inhaled steroids for chronic asthma in children and adults

Ciclesonide versus placebo for chronic asthma in adults and children

Clinical pathways for chronic cough in children

Clinical utility of limited channel sleep studies versus polysomnography for obstructive sleep apnea

Codeine versus placebo for chronic cough in children

Cognitive behavioural therapy (CBT) for adults and adolescents with asthma

Colchicine as an oral corticosteroid sparing agent for asthma

Combination fluticasone and salmeterol versus fixed dose combination budesonide and formoterol for chronic asthma in adults and children

Combination formoterol and budesonide as maintenance and reliever therapy versus combination inhaler maintenance for chronic asthma in adults and children

Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including inhaled steroid maintenance), for chronic asthma in adults and children

Combination formoterol and inhaled steroid versus beta₂-agonist as relief medication for chronic asthma in adults and children

Combination inhaled corticosteroids and long-acting beta-agonists for children and adults with bronchiectasis

Combination inhaled steroid and long-acting beta-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease

Combination inhaled steroid and long-acting beta2-agonist versus tiotropium for chronic obstructive pulmonary disease

Combined aclidinium bromide and long-acting beta2-agonist for chronic obstructive pulmonary disease (COPD)

Combined corticosteroid and long-acting beta-agonist in one inhaler versus inhaled corticosteroids alone for chronic obstructive pulmonary disease

Combined corticosteroid and long-acting beta-agonist in one inhaler versus placebo for chronic obstructive pulmonary disease

Combined corticosteroid and long-acting beta₂-agonist in one inhaler versus long-acting beta₂-agonists for chronic obstructive pulmonary disease

Combined inhaled anticholinergics and short-acting beta-agonists for initial treatment of acute asthma in children

Combined inhaled beta-agonist and anticholinergic agents for emergency management in adults with asthma

Commercial versus home-made spacers in delivering bronchodilator therapy for acute therapy in children

Computer and mobile technology interventions for self-management in chronic obstructive pulmonary disease

Continuous positive airway pressure delivery interfaces for obstructive sleep apnoea

Continuous positive airways pressure for obstructive sleep apnoea in adults

Continuous versus intermittent antibiotics for bronchiectasis

Continuous versus intermittent beta-agonists for acute asthma

Corticosteroids for acute severe asthma in hospitalised patients

Corticosteroids for hospitalised children with acute asthma

Corticosteroids for idiopathic pulmonary fibrosis

Corticosteroids for preventing relapse following acute exacerbations of asthma

Corticosteroids for pulmonary sarcoidosis

Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults

Culture-specific programs for children and adults from minority groups who have asthma

Cyclophosphamide for connective tissue disease–associated interstitial lung disease

Cyclosporin as an oral corticosteroid sparing agent in stable asthma

Dapsone as an oral corticosteroid sparing agent for asthma

Dehumidifiers for chronic asthma

Dietary marine fatty acids (fish oil) for asthma in adults and children

Dietary sodium manipulation and asthma

Different durations of corticosteroid therapy for exacerbations of chronic obstructive pulmonary disease

Different oral corticosteroid regimens for acute asthma

Digital interventions for the management of chronic obstructive pulmonary disease

Digital interventions to improve adherence to maintenance medication in asthma

Domiciliary oxygen for chronic obstructive pulmonary disease

Domiciliary oxygen for interstitial lung disease

Doppler trans-thoracic echocardiography for detection of pulmonary hypertension in adults

Doxapram for ventilatory failure due to exacerbations of chronic obstructive pulmonary disease

Drug therapy for obstructive sleep apnoea in adults

Dual antibiotics for bronchiectasis

Dual combination therapy versus long-acting bronchodilators alone for chronic obstructive pulmonary disease (COPD): a systematic review and network meta-analysis

Early emergency department treatment of acute asthma with systemic corticosteroids

Early use of inhaled corticosteroids in the emergency department treatment of acute asthma

Education interventions for adults who attend the emergency room for acute asthma

Educational interventions for asthma in children

Educational interventions for health professionals managing COPD in primary care

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea

Effects of opioid, hypnotic and sedating medications on sleep-disordered breathing in adults with obstructive sleep apnoea

Endothelin receptor antagonists for pulmonary arterial hypertension

Exercise training for bronchiectasis

Exercise-based rehabilitation programmes for pulmonary hypertension

Exhaled nitric oxide levels to guide treatment for adults with asthma

Exhaled nitric oxide levels to guide treatment for children with asthma

Factors influencing referral to and uptake and attendance of pulmonary rehabilitation for chronic obstructive pulmonary disease: a qualitative evidence synthesis of the experiences of service users, their families, and healthcare providers

Family therapy for asthma in children

Feather versus non-feather bedding for asthma

Fluticasone at different doses for chronic asthma in adults and children

Fluticasone versus 'extrafine' HFA-beclomethasone dipropionate for chronic asthma in adults and children

Fluticasone versus beclomethasone or budesonide for chronic asthma in adults and children

Fluticasone versus placebo for chronic asthma in adults and children

Formoterol versus short-acting beta-agonists as relief medication for adults and children with asthma

Galactomannan detection for invasive aspergillosis in immunocompromised patients

Galactomannan detection in broncho-alveolar lavage fluid for invasive aspergillosis in immunocompromised patients

Gastro-oesophageal reflux treatment for asthma in adults and children

Gastro-oesophageal reflux treatment for prolonged non-specific cough in children and adults

Glycopyrronium bromide for chronic obstructive pulmonary disease

Gold as an oral corticosteroid sparing agent in stable asthma

Guanylate cyclase stimulators for pulmonary hypertension

Head-to-head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease

Head-to-head trials of antibiotics for bronchiectasis

Health psychology interventions to improve adherence to maintenance therapies in asthma

Heliox for non-intubated acute asthma patients

Heliox for treatment of exacerbations of chronic obstructive pulmonary disease

Herbal interventions for chronic asthma in adults and children

High dose versus low dose inhaled corticosteroid as initial starting dose for asthma in adults and children

Holding chambers (spacers) versus nebulisers for beta-agonist treatment of acute asthma

Holding chambers versus nebulisers for inhaled steroids in chronic asthma

Home care by outreach nursing for chronic obstructive pulmonary disease

Home telemonitoring and remote feedback between clinic visits for asthma

Home-based educational interventions for children with asthma

Homeopathy for chronic asthma

Honey and lozenges for children with non-specific cough

Hospital at home for acute exacerbations of chronic obstructive pulmonary disease

House dust mite control measures for asthma

Immunostimulants versus placebo for preventing exacerbations in adults with chronic bronchitis or chronic obstructive pulmonary disease

Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis

Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children

Indacaterol, a once-daily beta-agonist, versus twice-daily beta-agonists or placebo for chronic obstructive pulmonary disease

Indigenous healthcare worker involvement for Indigenous adults and children with asthma

New

Individual-level interventions to reduce personal exposure to outdoor air pollution and their effects on long-term respiratory conditions

Indoor air modification interventions for prolonged non-specific cough in children

Influenza vaccine for children and adults with bronchiectasis

Influenza vaccine for chronic obstructive pulmonary disease (COPD)

Inhaled anticholinergics and short-acting beta-agonists versus short-acting beta2-agonists alone for children with acute asthma in hospital

Inhaled beta2-agonists for asthma in mechanically ventilated patients

Inhaled beta2-agonists for non-specific chronic cough in children

Inhaled corticosteroid effects on bone metabolism in asthma and mild chronic obstructive pulmonary disease

Inhaled corticosteroids compared to placebo for prevention of exercise induced bronchoconstriction

Inhaled corticosteroids for bronchiectasis

Inhaled corticosteroids for non-specific chronic cough in children

Inhaled corticosteroids for stable chronic obstructive pulmonary disease

Inhaled corticosteroids for subacute and chronic cough in adults

Inhaled corticosteroids for subacute cough in children

Inhaled corticosteroids in children with persistent asthma: dose-response effects on growth

Inhaled corticosteroids in children with persistent asthma: effects of different drugs and delivery devices on growth

Inhaled corticosteroids in children with persistent asthma: effects on growth

Inhaled corticosteroids versus long-acting beta-agonists for chronic obstructive pulmonary disease

Inhaled corticosteroids versus sodium cromoglycate in children and adults with asthma

Inhaled corticosteroids with combination inhaled long-acting beta-agonists and long-acting muscarinic antagonists for chronic obstructive pulmonary disease

Inhaled cromones for prolonged non-specific cough in children

Inhaled hyperosmolar agents for bronchiectasis

Inhaled magnesium sulfate in the treatment of acute asthma

Inhaled non-steroid anti-inflammatories for children and adults with bronchiectasis

Inhaled short acting beta2-agonist use in chronic asthma: regular versus as needed treatment

Inhaled short-acting beta2-agonists versus ipratropium for acute exacerbations of chronic obstructive pulmonary disease

Inhaled sodium cromoglycate for asthma in children

Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease

Inhaled steroids for acute asthma following emergency department discharge

Inhaled steroids for episodic viral wheeze of childhood

Updated

Inhaled steroids with and without regular formoterol for asthma: serious adverse events

Inhaled steroids with and without regular salmeterol for asthma: serious adverse events

Inhaled versus oral steroids for adults with chronic asthma

Injection allergen immunotherapy for asthma

Inspiratory muscle training for asthma

Integrated disease management interventions for patients with chronic obstructive pulmonary disease

Intermittent inhaled corticosteroid therapy versus placebo for persistent asthma in children and adults

Intermittent prophylactic antibiotics for bronchiectasis

Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults

Interventions for autumn exacerbations of asthma in children

Interventions for bronchiectasis: an overview of Cochrane systematic reviews

Interventions for educating children who are at risk of asthma-related emergency department attendance

Interventions for enhancing adherence to treatment in adults with bronchiectasis

Interventions for escalation of therapy for acute exacerbations of asthma in children: an overview of Cochrane Reviews

Interventions for managing asthma in pregnancy

Interventions for primary (intrinsic) tracheomalacia in children

Interventions for promoting physical activity in people with COPD

Interventions for sexual dysfunction in people with chronic obstructive pulmonary disease (COPD)

Interventions to improve adherence to inhaled steroids for asthma

Interventions to improve adherence to pharmacological therapy for chronic obstructive pulmonary disease (COPD)

Interventions to improve inhaler technique for people with asthma

Interventions to promote referral, uptake and adherence to pulmonary rehabilitation for people with chronic obstructive pulmonary disease (COPD)

Intra-pleural fibrinolytic therapy versus conservative management in the treatment of adult parapneumonic effusions and empyema

Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for acute asthma

Intranasal corticosteroids for asthma control in people with coexisting asthma and rhinitis

Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease

Intravenous aminophylline for acute severe asthma in children over two years receiving inhaled bronchodilators

Intravenous beta2-agonists for acute asthma in the emergency department

Intravenous beta₂-agonists versus intravenous aminophylline for acute asthma

Intravenous magnesium sulfate for treating adults with acute asthma in the emergency department

Intravenous magnesium sulfate for treating children with acute asthma in the emergency department

Ionisers for chronic asthma

Ipratropium bromide versus long-acting beta-2 agonists for stable chronic obstructive pulmonary disease

Ipratropium bromide versus short acting beta-2 agonists for stable chronic obstructive pulmonary disease

Ketamine for management of acute exacerbations of asthma in children

Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children

Lay-led and peer support interventions for adolescents with asthma

Leukotriene receptor antagonist for prolonged non-specific cough in children

Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children

Leukotriene receptor antagonists for non-cystic fibrosis bronchiectasis

Leukotriene receptor antagonists in addition to usual care for acute asthma in adults and children

Lifestyle modification for obstructive sleep apnoea

Limited (information only) patient education programs for adults with asthma

Long-acting beta-agonist in addition to tiotropium versus either tiotropium or long-acting beta-agonist alone for chronic obstructive pulmonary disease

Long-acting beta-agonists for chronic obstructive pulmonary disease

Long-acting beta2-agonists as an inhaled corticosteroid-sparing agent for chronic asthma in adults and children

Long-acting beta2-agonists for bronchiectasis

Long-acting beta2-agonists for chronic asthma in adults and children where background therapy contains varied or no inhaled corticosteroid

Long-acting beta2-agonists for poorly reversible chronic obstructive pulmonary disease

Long-acting beta2-agonists versus theophylline for maintenance treatment of asthma

Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis

Long-acting muscarinic antagonist (LAMA) plus long-acting beta-agonist (LABA) versus LABA plus inhaled corticosteroid (ICS) for stable chronic obstructive pulmonary disease (COPD)

Long-acting muscarinic antagonists (LAMA) added to combination long-acting beta-agonists and inhaled corticosteroids (LABA/ICS) versus LABA/ICS for adults with asthma

Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus addition of long-acting beta-agonists (LABA) for adults with asthma

Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus higher dose ICS for adults with asthma

Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus the same dose of ICS alone for adults with asthma

Lung volume reduction surgery for diffuse emphysema

Macrolide antibiotics for bronchiectasis

Macrolides for chronic asthma

Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease

Magnesium sulfate for treating exacerbations of acute asthma in the emergency department

Maintenance pulmonary rehabilitation for chronic obstructive pulmonary disease

Manual therapy for asthma

Mast-cell stabilising agents to prevent exercise-induced bronchoconstriction

Methotrexate as a steroid sparing agent for asthma in adults

Methylxanthines for exacerbations of chronic obstructive pulmonary disease

Methylxanthines for prolonged non-specific cough in children

Mono and multifaceted inhalant and/or food allergen reduction interventions for preventing asthma in children at high risk of developing asthma

Monosodium glutamate avoidance for chronic asthma in adults and children

Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease

Mucolytics for bronchiectasis

Myofunctional therapy (oropharyngeal exercises) for obstructive sleep apnoea

New

Myofunctional therapy (oropharyngeal exercises) for obstructive sleep apnoea

Nebulised morphine for severe interstitial lung disease

Nedocromil sodium for chronic asthma in children

Nedocromil sodium for preventing exercise-induced bronchoconstriction

Nedocromil sodium versus sodium cromoglycate for preventing exercise-induced bronchoconstriction

Neuromuscular electrostimulation for adults with chronic obstructive pulmonary disease

Nocturnal non-invasive positive pressure ventilation for stable chronic obstructive pulmonary disease

Non-invasive positive airway pressure therapy for improving erectile dysfunction in men with obstructive sleep apnoea

Non-invasive positive airway pressure therapy for obesity hypoventilation syndrome in adults

Non-invasive positive pressure ventilation for acute asthma in children

Non-invasive positive pressure ventilation for central sleep apnoea in adults

Non-invasive positive pressure ventilation for treatment of respiratory failure due to severe acute exacerbations of asthma

Non-invasive ventilation during exercise training for people with chronic obstructive pulmonary disease

Non-invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease

Non-pharmaceutical management of respiratory morbidity in children with severe global developmental delay

Non-pharmacological management interventions for COPD: an overview of Cochrane systematic reviews

Non-steroid agents for idiopathic pulmonary fibrosis

Nurse versus physician-led care for the management of asthma

Nurse-led versus doctor-led care for bronchiectasis

Nutritional supplementation for stable chronic obstructive pulmonary disease

Omalizumab for asthma in adults and children

Once daily long-acting beta2-agonists and long-acting muscarinic antagonists in a combined inhaler versus placebo for chronic obstructive pulmonary disease

Once-daily LABA/ICS combined inhalers versus inhaled long-acting beta2-agonists for people with chronic obstructive pulmonary disease (COPD)

Once-daily long-acting beta₂-agonists/inhaled corticosteroids combined inhalers versus inhaled long-acting muscarinic antagonists for people with chronic obstructive pulmonary disease

Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease

Options for self-management education for adults with asthma

Oral appliances for obstructive sleep apnoea

Oral appliances for obstructive sleep apnoea

Oral corticosteroids for bronchiectasis (stable and acute exacerbations)

Oral corticosteroids for stable chronic obstructive pulmonary disease

Oral methylxanthines for bronchiectasis

Oral non steroid anti-inflammatories for children and adults with bronchiectasis

Oral theophylline for chronic obstructive pulmonary disease

Oral versus inhaled antibiotics for bronchiectasis

Oral xanthine derivatives (theophylline and doxofylline) for patients with stable chronic obstructive pulmonary disease (COPD)

Oral xanthines as maintenance treatment for asthma in children

Oxatomide for stable asthma in adults and children

Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen therapy

Oxygen therapy during exercise training in chronic obstructive pulmonary disease

Oxygen therapy in the pre-hospital setting for acute exacerbations of chronic obstructive pulmonary disease

Parent-initiated oral corticosteroid therapy for intermittent wheezing illnesses in children

Patient- and parent-initiated oral steroids for asthma exacerbations

Personalised asthma action plans for adults with asthma

Pet allergen control measures for allergic asthma in children and adults

Pharmacological treatment for central sleep apnoea in adults

Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary disease

Phosphodiesterase 5 inhibitors for pulmonary hypertension

Phosphodiesterase 5 inhibitors for pulmonary hypertension

Physical training for asthma

Physical training for bronchiectasis

Pneumococcal vaccine for asthma

Pneumococcal vaccines for children and adults with bronchiectasis

Pneumococcal vaccines for preventing pneumonia in chronic obstructive pulmonary disease

Positional therapy for obstructive sleep apnoea

Positive expiratory pressure therapy versus other airway clearance techniques for bronchiectasis

Pressure modification for improving usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea

Pressure setting and titration strategies for improving usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea

Pressurised metered dose inhalers versus all other hand-held inhaler devices to deliver beta-2 agonist bronchodilators for non-acute asthma

Pressurised metered-dose inhalers versus all other hand-held inhalers devices to deliver bronchodilators for chronic obstructive pulmonary disease

Primary care based clinics for asthma

Prognosis of adults with idiopathic pulmonary fibrosis without treatment or without effective therapies

Prolonged antibiotics for non-cystic fibrosis bronchiectasis in children and adults

Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD)

Prophylactic antibiotics for adults with chronic obstructive pulmonary disease: a network meta-analysis

Prostacyclin for pulmonary arterial hypertension

Prostacyclin for pulmonary hypertension in adults

Proton pump inhibitors for chronic obstructive pulmonary disease

Psychological interventions for adults with asthma

New

Psychological interventions for asthma in children and adolescents

Psychological interventions for children with asthma

Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease

Pulmonary rehabilitation for chronic obstructive pulmonary disease

Pulmonary rehabilitation for interstitial lung disease

Pulmonary rehabilitation for older adults with asthma

Pulmonary rehabilitation using minimal equipment for people with chronic obstructive pulmonary disease (COPD)

Pulse oximeters to self monitor oxygen saturation levels as part of a personalised asthma action plan for people with asthma

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an inhaled corticosteroid for chronic asthma: serious adverse events

Regular treatment with formoterol for chronic asthma: serious adverse events

Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events

Regular treatment with long acting beta agonists versus daily regular treatment with short acting beta agonists in adults and children with stable asthma

Regular treatment with salmeterol for chronic asthma: serious adverse events

Remote versus face-to-face check-ups for asthma

Respite care for young people living with life-limiting conditions

Restriction of oral intake of water for aspiration lung disease in children

Safety of regular formoterol or salmeterol in adults with asthma: an overview of Cochrane reviews

Safety of regular formoterol or salmeterol in children with asthma: an overview of Cochrane reviews

School-based self-management interventions for asthma in children and adolescents: a mixed methods systematic review

Selenium supplementation for asthma

Self management for patients with chronic obstructive pulmonary disease

Self-management education and regular practitioner review for adults with asthma

Self-management for bronchiectasis

Self-management interventions including action plans for exacerbations versus usual care in patients with chronic obstructive pulmonary disease

Shared decision-making for people with asthma

Short acting beta2-agonists for bronchiectasis

Short acting beta2-agonists for recurrent wheeze in children under two years of age

Short courses of antibiotics for children and adults with bronchiectasis

Short-acting beta2-agonists for stable chronic obstructive pulmonary disease

Short-term ambulatory oxygen for chronic obstructive pulmonary disease

Singing for adults with chronic obstructive pulmonary disease

Singing for children and adults with bronchiectasis

Smartphone and tablet self management apps for asthma

Smoking cessation for chronic obstructive pulmonary disease

Smoking cessation for people with chronic obstructive pulmonary disease

Speech and language therapy for management of chronic cough

Speleotherapy for asthma

Statins for asthma

Statins for bronchiectasis

Statins versus placebo for people with chronic obstructive pulmonary disease

Stepping down the dose of inhaled corticosteroids for adults with asthma

Stopping long-acting beta-agonists (LABA) for adults with asthma well controlled by LABA and inhaled corticosteroids

Stopping long-acting beta2-agonists (LABA) for children with asthma well controlled on LABA and inhaled corticosteroids

Sublingual immunotherapy for asthma

Surgery for obstructive sleep apnoea in adults

Surgery for obstructive sleep apnoea in adults

Surgery versus non-surgical treatment for bronchiectasis

Swimming training for asthma in children and adolescents aged 18 years and under

Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease

Systemic steroids versus placebo for acute wheeze in preschool aged children

Tai Chi for chronic obstructive pulmonary disease (COPD)

Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults

Tailored interventions based on sputum eosinophils versus clinical symptoms for asthma in children and adults

Targeted interventions and approaches to care for people living with chronic obstructive pulmonary disease and at least one other long-term condition: a mixed methods review

Tartrazine exclusion for allergic asthma

Telehealthcare for asthma

Telehealthcare for chronic obstructive pulmonary disease

Telehealthcare for remote monitoring and consultations for people with chronic obstructive pulmonary disease (COPD)

Telerehabilitation for chronic respiratory disease

The effect of adding inhaled corticosteroids to tiotropium and long-acting beta₂-agonists for chronic obstructive pulmonary disease

Tiotropium for stable chronic obstructive pulmonary disease

Tiotropium versus ipratropium bromide for chronic obstructive pulmonary disease

Tiotropium versus long-acting beta-agonists for stable chronic obstructive pulmonary disease

Tiotropium versus placebo for chronic obstructive pulmonary disease

Tonsillectomy or adenotonsillectomy versus non-surgical management for obstructive sleep-disordered breathing in children

Tonsillectomy versus tonsillotomy for sleep-disordered breathing in children

Treatment of obstructive sleep apnoea for chronic cough in children

Troleandomycin as an oral corticosteroid sparing agent in stable asthma

Umeclidinium bromide versus placebo for people with chronic obstructive pulmonary disease (COPD)

Unsupervised exercise training versus no exercise training for chronic obstructive pulmonary disease

Upper limb exercise training for COPD

Vaccines for preventing influenza in people with asthma

Vilanterol and fluticasone furoate for asthma

Vitamin C for asthma and exercise-induced bronchoconstriction

Vitamin D for the management of asthma

Vitamin D for the management of chronic obstructive pulmonary disease

Vitamin D supplementation in pregnant or breastfeeding women or young children for preventing asthma

Vitamins C and E for asthma and exercise-induced bronchoconstriction

Water-based exercise for adults with asthma

Water-based exercise training for chronic obstructive pulmonary disease

Weight loss intervention through lifestyle modification or pharmacotherapy for obstructive sleep apnoea in adults

Weight loss interventions for chronic asthma

Updated

Workplace interventions for treatment of occupational asthma

Written action plans for asthma in children

Written emotional disclosure for asthma

Yoga for asthma

By subtopic:

Allergic rhinitis (1)

Intranasal corticosteroids for asthma control in people with coexisting asthma and rhinitis

Alpha 1 - antitrypsin deficiency (1)

Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease

Aspergillosis, allergic bronchopulmonary (3)

Azoles for allergic bronchopulmonary aspergillosis associated with asthma

Galactomannan detection for invasive aspergillosis in immunocompromised patients

Galactomannan detection in broncho-alveolar lavage fluid for invasive aspergillosis in immunocompromised patients

Asthma, acute - pharmacotherapy (48)

Anti-bacterial agents (1)

Antibiotics for exacerbations of asthma

Anticholinergics (5)

Anticholinergic therapy for acute asthma in children

Inhaled anticholinergics and short-acting beta-agonists versus short-acting beta2-agonists alone for children with acute asthma in hospital

Combined inhaled beta-agonist and anticholinergic agents for emergency management in adults with asthma

Combined inhaled anticholinergics and short-acting beta-agonists for initial treatment of acute asthma in children

Interventions for escalation of therapy for acute exacerbations of asthma in children: an overview of Cochrane Reviews (protocol stage)

Epinephrine (1)

Interventions for escalation of therapy for acute exacerbations of asthma in children: an overview of Cochrane Reviews (protocol stage)

Leukotriene antagonists (1)

Leukotriene receptor antagonists in addition to usual care for acute asthma in adults and children

Beta-agonists (13)

Addition of intravenous beta₂-agonists to inhaled beta₂-agonists for acute asthma

Inhaled anticholinergics and short-acting beta-agonists versus short-acting beta2-agonists alone for children with acute asthma in hospital

Combined inhaled beta-agonist and anticholinergic agents for emergency management in adults with asthma

Combined inhaled anticholinergics and short-acting beta-agonists for initial treatment of acute asthma in children

Commercial versus home-made spacers in delivering bronchodilator therapy for acute therapy in children

Continuous versus intermittent beta-agonists for acute asthma

Addition of intravenous aminophylline to inhaled beta₂-agonists in adults with acute asthma

Holding chambers (spacers) versus nebulisers for beta-agonist treatment of acute asthma

Inhaled beta2-agonists for asthma in mechanically ventilated patients

Interventions for escalation of therapy for acute exacerbations of asthma in children: an overview of Cochrane Reviews (protocol stage)

Intravenous aminophylline for acute severe asthma in children over two years receiving inhaled bronchodilators

Intravenous beta₂-agonists versus intravenous aminophylline for acute asthma

Intravenous beta2-agonists for acute asthma in the emergency department

Inhaler devices and delivery therapy (5)

Commercial versus home-made spacers in delivering bronchodilator therapy for acute therapy in children

Heliox for non-intubated acute asthma patients

Holding chambers (spacers) versus nebulisers for beta-agonist treatment of acute asthma

Inhaled beta2-agonists for asthma in mechanically ventilated patients

Interventions to improve inhaler technique for people with asthma

Magnesium sulfate (5)

Intravenous magnesium sulfate for treating adults with acute asthma in the emergency department

Intravenous magnesium sulfate for treating children with acute asthma in the emergency department

Interventions for escalation of therapy for acute exacerbations of asthma in children: an overview of Cochrane Reviews (protocol stage)

Inhaled magnesium sulfate in the treatment of acute asthma

Magnesium sulfate for treating exacerbations of acute asthma in the emergency department

Other bronchodilators (2)

Interventions for escalation of therapy for acute exacerbations of asthma in children: an overview of Cochrane Reviews (protocol stage)

Ketamine for management of acute exacerbations of asthma in children

Steroids, inhaled (4)

Early use of inhaled corticosteroids in the emergency department treatment of acute asthma

Increased versus stable doses of inhaled corticosteroids for exacerbations of chronic asthma in adults and children

Inhaled steroids for acute asthma following emergency department discharge

Interventions to improve adherence to inhaled steroids for asthma

Steroids, oral and systemic (8)

Corticosteroids for acute severe asthma in hospitalised patients

Corticosteroids for hospitalised children with acute asthma

Corticosteroids for preventing relapse following acute exacerbations of asthma

Different oral corticosteroid regimens for acute asthma

Early emergency department treatment of acute asthma with systemic corticosteroids

Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for acute asthma

Patient- and parent-initiated oral steroids for asthma exacerbations

Systemic steroids versus placebo for acute wheeze in preschool aged children (protocol stage)

Addition of intravenous aminophylline to inhaled beta₂-agonists in adults with acute asthma

Intravenous aminophylline for acute severe asthma in children over two years receiving inhaled bronchodilators

Intravenous beta₂-agonists versus intravenous aminophylline for acute asthma

Asthma, acute - non-pharmacotherapy (8)

Pulse oximeters to self monitor oxygen saturation levels as part of a personalised asthma action plan for people with asthma

Personalised asthma action plans for adults with asthma

Ventilation (3)

Interventions for escalation of therapy for acute exacerbations of asthma in children: an overview of Cochrane Reviews (protocol stage)

Non-invasive positive pressure ventilation for acute asthma in children

Non-invasive positive pressure ventilation for treatment of respiratory failure due to severe acute exacerbations of asthma

Asthma education for school staff

Education interventions for adults who attend the emergency room for acute asthma

Interventions for educating children who are at risk of asthma-related emergency department attendance

Asthma, chronic - pharmacotherapy (164)

Adverse effects of treatment (6)

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an inhaled corticosteroid for chronic asthma: serious adverse events

Regular treatment with formoterol for chronic asthma: serious adverse events

Regular treatment with salmeterol for chronic asthma: serious adverse events

Inhaled steroids with and without regular salmeterol for asthma: serious adverse events

Inhaled steroids with and without regular formoterol for asthma: serious adverse events

Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events

Anti-inflammatory agents, non-steroidal (1)

Macrolides for chronic asthma

Antibodies, monoclonal (3)

Anti-interleukin-13 and anti-interleukin-4 agents versus placebo, anti-interleukin-5 or anti-immunoglobulin-E agents, for children and adults with asthma (protocol stage)

Anti-IL5 therapies for asthma

Omalizumab for asthma in adults and children

Beta-agonists, long-acting (26)

Addition of long-acting beta-agonists to inhaled corticosteroids for chronic asthma in children

Combination fluticasone and salmeterol versus fixed dose combination budesonide and formoterol for chronic asthma in adults and children

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an inhaled corticosteroid for chronic asthma: serious adverse events

Long-acting muscarinic antagonists (LAMA) added to combination long-acting beta-agonists and inhaled corticosteroids (LABA/ICS) versus LABA/ICS for adults with asthma

Regular treatment with formoterol for chronic asthma: serious adverse events

Regular treatment with salmeterol for chronic asthma: serious adverse events

Addition to inhaled corticosteroids of long-acting beta-agonists versus anti-leukotrienes for chronic asthma

Combination formoterol and budesonide as maintenance and reliever therapy versus combination inhaler maintenance for chronic asthma in adults and children

Combination formoterol and inhaled steroid versus beta₂-agonist as relief medication for chronic asthma in adults and children

Formoterol versus short-acting beta-agonists as relief medication for adults and children with asthma

Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including inhaled steroid maintenance), for chronic asthma in adults and children

Inhaled steroids with and without regular salmeterol for asthma: serious adverse events

Long-acting beta2-agonists as an inhaled corticosteroid-sparing agent for chronic asthma in adults and children

Long-acting beta2-agonists for chronic asthma in adults and children where background therapy contains varied or no inhaled corticosteroid

Addition of long-acting beta2-agonists to inhaled corticosteroids versus same dose inhaled corticosteroids for chronic asthma in adults and children

Long-acting beta2-agonists versus theophylline for maintenance treatment of asthma

Safety of regular formoterol or salmeterol in adults with asthma: an overview of Cochrane reviews

Safety of regular formoterol or salmeterol in children with asthma: an overview of Cochrane reviews

Inhaled steroids with and without regular formoterol for asthma: serious adverse events

Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events

Regular treatment with long acting beta agonists versus daily regular treatment with short acting beta agonists in adults and children with stable asthma

Stopping long-acting beta2-agonists (LABA) for children with asthma well controlled on LABA and inhaled corticosteroids

Addition of long-acting beta2-agonists to inhaled steroids versus higher dose inhaled steroids in adults and children with persistent asthma

Addition of long-acting beta2-agonists to inhaled steroids as first line therapy for persistent asthma in steroid-naive adults and children

Vilanterol and fluticasone furoate for asthma

Stopping long-acting beta-agonists (LABA) for adults with asthma well controlled by LABA and inhaled corticosteroids

Beta-agonists, short-acting (8)

Beta-agonists for exercise-induced asthma

Leukotriene receptor antagonists in addition to usual care for acute asthma in adults and children

Combination formoterol and inhaled steroid versus beta₂-agonist as relief medication for chronic asthma in adults and children

Formoterol versus short-acting beta-agonists as relief medication for adults and children with asthma

Inhaled short acting beta2-agonist use in chronic asthma: regular versus as needed treatment

Pressurised metered dose inhalers versus all other hand-held inhaler devices to deliver beta-2 agonist bronchodilators for non-acute asthma

Regular treatment with long acting beta agonists versus daily regular treatment with short acting beta agonists in adults and children with stable asthma

Short acting beta2-agonists for recurrent wheeze in children under two years of age

Management in pregnancy (1)

Interventions for managing asthma in pregnancy

Muscarinic antagonists (4)

Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus the same dose of ICS alone for adults with asthma

Long-acting muscarinic antagonists (LAMA) added to combination long-acting beta-agonists and inhaled corticosteroids (LABA/ICS) versus LABA/ICS for adults with asthma

Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus higher dose ICS for adults with asthma

Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus addition of long-acting beta-agonists (LABA) for adults with asthma

Mast-cell stabilising agents to prevent exercise-induced bronchoconstriction

Phosphodiesterases (0)

Statins for asthma (protocol stage)

Steroids, inhaled (49)

Addition of long-acting beta-agonists to inhaled corticosteroids for chronic asthma in children

Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children

Beclomethasone at different doses for chronic asthma

Budesonide at different doses for chronic asthma

Budesonide versus placebo for chronic asthma in children and adults

Intermittent inhaled corticosteroid therapy versus placebo for persistent asthma in children and adults

Ciclesonide versus other inhaled corticosteroids for chronic asthma in children

Ciclesonide versus other inhaled steroids for chronic asthma in children and adults

Ciclesonide versus placebo for chronic asthma in adults and children

Combination fluticasone and salmeterol versus fixed dose combination budesonide and formoterol for chronic asthma in adults and children

Inhaled corticosteroids in children with persistent asthma: effects on growth

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an inhaled corticosteroid for chronic asthma: serious adverse events

Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus the same dose of ICS alone for adults with asthma

Long-acting muscarinic antagonists (LAMA) added to combination long-acting beta-agonists and inhaled corticosteroids (LABA/ICS) versus LABA/ICS for adults with asthma

Inhaled corticosteroids in children with persistent asthma: dose-response effects on growth

Fluticasone at different doses for chronic asthma in adults and children

Fluticasone versus beclomethasone or budesonide for chronic asthma in adults and children

Fluticasone versus placebo for chronic asthma in adults and children

Combination formoterol and budesonide as maintenance and reliever therapy versus combination inhaler maintenance for chronic asthma in adults and children

Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus higher dose ICS for adults with asthma

Combination formoterol and inhaled steroid versus beta₂-agonist as relief medication for chronic asthma in adults and children

High dose versus low dose inhaled corticosteroid as initial starting dose for asthma in adults and children

Holding chambers versus nebulisers for inhaled steroids in chronic asthma

Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including inhaled steroid maintenance), for chronic asthma in adults and children

Beclomethasone versus placebo for chronic asthma

Inhaled corticosteroid effects on bone metabolism in asthma and mild chronic obstructive pulmonary disease

Inhaled corticosteroids versus sodium cromoglycate in children and adults with asthma

Fluticasone versus 'extrafine' HFA-beclomethasone dipropionate for chronic asthma in adults and children

Inhaled steroids for episodic viral wheeze of childhood

Inhaled steroids with and without regular salmeterol for asthma: serious adverse events

Inhaled versus oral steroids for adults with chronic asthma

Addition of anti-leukotriene agents to inhaled corticosteroids for adults and adolescents with persistent asthma

Addition of anti-leukotriene agents to inhaled corticosteroids in children with persistent asthma

Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus addition of long-acting beta-agonists (LABA) for adults with asthma

Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults

Addition of long-acting beta2-agonists to inhaled corticosteroids versus same dose inhaled corticosteroids for chronic asthma in adults and children

Safety of regular formoterol or salmeterol in adults with asthma: an overview of Cochrane reviews

Safety of regular formoterol or salmeterol in children with asthma: an overview of Cochrane reviews

Inhaled steroids with and without regular formoterol for asthma: serious adverse events

Stepping down the dose of inhaled corticosteroids for adults with asthma

Stopping long-acting beta2-agonists (LABA) for children with asthma well controlled on LABA and inhaled corticosteroids

Addition of anti-leukotriene agents to inhaled corticosteroids for chronic asthma

Addition of long-acting beta2-agonists to inhaled steroids versus higher dose inhaled steroids in adults and children with persistent asthma

Addition of long-acting beta2-agonists to inhaled steroids as first line therapy for persistent asthma in steroid-naive adults and children

Beclomethasone for asthma in children: effects on linear growth

Beclomethasone versus budesonide for chronic asthma

Vilanterol and fluticasone furoate for asthma

Stopping long-acting beta-agonists (LABA) for adults with asthma well controlled by LABA and inhaled corticosteroids

Inhaled corticosteroids in children with persistent asthma: effects of different drugs and delivery devices on growth

Steroids, oral (3)

Inhaled steroids for episodic viral wheeze of childhood

Inhaled versus oral steroids for adults with chronic asthma

Parent-initiated oral corticosteroid therapy for intermittent wheezing illnesses in children

Steroids, intranasal (1)

Intranasal corticosteroids for asthma control in people with coexisting asthma and rhinitis

Combination and additive therapies (22)

Addition of long-acting beta-agonists to inhaled corticosteroids for chronic asthma in children

Combination fluticasone and salmeterol versus fixed dose combination budesonide and formoterol for chronic asthma in adults and children

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an inhaled corticosteroid for chronic asthma: serious adverse events

Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus the same dose of ICS alone for adults with asthma

Long-acting muscarinic antagonists (LAMA) added to combination long-acting beta-agonists and inhaled corticosteroids (LABA/ICS) versus LABA/ICS for adults with asthma

Addition to inhaled corticosteroids of long-acting beta-agonists versus anti-leukotrienes for chronic asthma

Combination formoterol and budesonide as maintenance and reliever therapy versus combination inhaler maintenance for chronic asthma in adults and children

Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus higher dose ICS for adults with asthma

Combination formoterol and inhaled steroid versus beta₂-agonist as relief medication for chronic asthma in adults and children

Combination formoterol and budesonide as maintenance and reliever therapy versus current best practice (including inhaled steroid maintenance), for chronic asthma in adults and children

Inhaled steroids with and without regular salmeterol for asthma: serious adverse events

Long-acting muscarinic antagonists (LAMA) added to inhaled corticosteroids (ICS) versus addition of long-acting beta-agonists (LABA) for adults with asthma

Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children

Addition of long-acting beta2-agonists to inhaled corticosteroids versus same dose inhaled corticosteroids for chronic asthma in adults and children

Safety of regular formoterol or salmeterol in adults with asthma: an overview of Cochrane reviews

Safety of regular formoterol or salmeterol in children with asthma: an overview of Cochrane reviews

Inhaled steroids with and without regular formoterol for asthma: serious adverse events

Stopping long-acting beta2-agonists (LABA) for children with asthma well controlled on LABA and inhaled corticosteroids

Addition of long-acting beta2-agonists to inhaled steroids versus higher dose inhaled steroids in adults and children with persistent asthma

Addition of long-acting beta2-agonists to inhaled steroids as first line therapy for persistent asthma in steroid-naive adults and children

Vilanterol and fluticasone furoate for asthma

Stopping long-acting beta-agonists (LABA) for adults with asthma well controlled by LABA and inhaled corticosteroids

Anti-bacterial agents (1)

Macrolides for chronic asthma

Antihistamines (1)

Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children

Allergen immunotherapy (2)

Injection allergen immunotherapy for asthma

Sublingual immunotherapy for asthma

Anticholinergics (3)

Anticholinergic agents for chronic asthma in adults

Anticholinergic drugs for wheeze in children under the age of two years

Anticholinergic therapy for chronic asthma in children over two years of age

Cardioselective beta-blockers (1)

Cardioselective beta-blockers for reversible airway disease

Inhaled corticosteroids versus sodium cromoglycate in children and adults with asthma

Nedocromil sodium for chronic asthma in children

Nedocromil sodium for preventing exercise-induced bronchoconstriction

Nedocromil sodium versus sodium cromoglycate for preventing exercise-induced bronchoconstriction

Inhaled sodium cromoglycate for asthma in children

Gastro-oesophogeal reflux treatment (1)

Gastro-oesophageal reflux treatment for asthma in adults and children

Histamine antagonists (1)

Oxatomide for stable asthma in adults and children

Inhaler devices and delivery of therapy (2)

Holding chambers versus nebulisers for inhaled steroids in chronic asthma

Pressurised metered dose inhalers versus all other hand-held inhaler devices to deliver beta-2 agonist bronchodilators for non-acute asthma

Leukotriene antagonists (7)

Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children

Antileukotriene agents compared with placebo in children and adults with mild asthma (protocol stage)

Addition to inhaled corticosteroids of long-acting beta-agonists versus anti-leukotrienes for chronic asthma

Addition of anti-leukotriene agents to inhaled corticosteroids for adults and adolescents with persistent asthma

Addition of anti-leukotriene agents to inhaled corticosteroids in children with persistent asthma

Addition of anti-leukotriene agents to inhaled corticosteroids for chronic asthma

Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children

Steroid sparing agents (10)

Azathioprine as an oral corticosteroid sparing agent for asthma

Chloroquine as a steroid sparing agent for asthma

Colchicine as an oral corticosteroid sparing agent for asthma

Cyclosporin as an oral corticosteroid sparing agent in stable asthma

Dapsone as an oral corticosteroid sparing agent for asthma

Gold as an oral corticosteroid sparing agent in stable asthma

Long-acting beta2-agonists as an inhaled corticosteroid-sparing agent for chronic asthma in adults and children

Methotrexate as a steroid sparing agent for asthma in adults

Omalizumab for asthma in adults and children

Troleandomycin as an oral corticosteroid sparing agent in stable asthma

Pneumococcal vaccine for asthma

Vaccines for preventing influenza in people with asthma

Long-acting beta2-agonists versus theophylline for maintenance treatment of asthma

Oral xanthines as maintenance treatment for asthma in children

Asthma, chronic - non-pharmacotherapy (92)

Exhaled nitric oxide levels to guide treatment for children with asthma

Exhaled nitric oxide levels to guide treatment for adults with asthma

Tailored interventions based on sputum eosinophils versus clinical symptoms for asthma in children and adults

Complementary therapies (7)

Acupuncture for chronic asthma

Herbal interventions for chronic asthma in adults and children

Homeopathy for chronic asthma

Ionisers for chronic asthma

Manual therapy for asthma

Speleotherapy for asthma

Yoga for asthma

Delivery of care (6)

Shared decision-making for people with asthma

Smartphone and tablet self management apps for asthma

Indigenous healthcare worker involvement for Indigenous adults and children with asthma

Nurse versus physician-led care for the management of asthma

Primary care based clinics for asthma

Lay-led and peer support interventions for adolescents with asthma

Diet therapy and nutrition support (14)

Calorie controlled diet for chronic asthma

Dietary marine fatty acids (fish oil) for asthma in adults and children

Weight loss interventions for chronic asthma

Dietary sodium manipulation and asthma

Herbal interventions for chronic asthma in adults and children

Mono and multifaceted inhalant and/or food allergen reduction interventions for preventing asthma in children at high risk of developing asthma

Monosodium glutamate avoidance for chronic asthma in adults and children

Selenium supplementation for asthma

Tartrazine exclusion for allergic asthma

Caffeine for asthma

Vitamin C for asthma and exercise-induced bronchoconstriction

Vitamin D supplementation in pregnant or breastfeeding women or young children for preventing asthma (protocol stage)

Vitamin D for the management of asthma

Vitamins C and E for asthma and exercise-induced bronchoconstriction

Disease management and monitoring (26)

Remote versus face-to-face check-ups for asthma

Asthma self management education with either regular healthcare professional review or written action plans or both in adults (protocol stage)

Exhaled nitric oxide levels to guide treatment for children with asthma

Shared decision-making for people with asthma

Smartphone and tablet self management apps for asthma

Culture-specific programs for children and adults from minority groups who have asthma

Dehumidifiers for chronic asthma

Digital interventions to improve adherence to maintenance medication in asthma (protocol stage)

Weight loss interventions for chronic asthma

House dust mite control measures for asthma

Exhaled nitric oxide levels to guide treatment for adults with asthma

Feather versus non-feather bedding for asthma

Home-based educational interventions for children with asthma

Indigenous healthcare worker involvement for Indigenous adults and children with asthma

Ionisers for chronic asthma

Mono and multifaceted inhalant and/or food allergen reduction interventions for preventing asthma in children at high risk of developing asthma

Options for self-management education for adults with asthma

Pet allergen control measures for allergic asthma in children and adults

Self-management education and regular practitioner review for adults with asthma

Lay-led and peer support interventions for adolescents with asthma

Tailored interventions based on sputum eosinophils versus clinical symptoms for asthma in children and adults

Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults

Telehealthcare for asthma

Written action plans for asthma in children

Home telemonitoring and remote feedback between clinic visits for asthma

Personalised asthma action plans for adults with asthma

School-based self-management interventions for asthma in children and adolescents: a mixed methods systematic review

Remote versus face-to-face check-ups for asthma

Asthma education for school staff

Asthma self management education with either regular healthcare professional review or written action plans or both in adults (protocol stage)

Caseworker-assigned discharge plans to prevent hospital readmission for acute exacerbations in children with chronic respiratory illness

Culture-specific programs for children and adults from minority groups who have asthma

Education interventions for adults who attend the emergency room for acute asthma

Educational interventions for asthma in children

Home-based educational interventions for children with asthma

Limited (information only) patient education programs for adults with asthma

Options for self-management education for adults with asthma

Self-management education and regular practitioner review for adults with asthma

Lay-led and peer support interventions for adolescents with asthma

Home telemonitoring and remote feedback between clinic visits for asthma

Interventions for educating children who are at risk of asthma-related emergency department attendance

Environment exposure reduction (1)

Individual-level interventions to reduce personal exposure to outdoor air pollution and their effects on long-term respiratory conditions (protocol stage)

Invasive therapeutic procedures (1)

Bronchial thermoplasty for moderate or severe persistent asthma in adults

Management in pregnancy (1)

Interventions for managing asthma in pregnancy

Psychotherapy (7)

Cognitive behavioural therapy (CBT) for adults and adolescents with asthma

Family therapy for asthma in children

Health psychology interventions to improve adherence to maintenance therapies in asthma (protocol stage)

Psychological interventions for adults with asthma

Psychological interventions for asthma in children and adolescents (protocol stage)

Psychological interventions for children with asthma

Written emotional disclosure for asthma

Physical therapy (10)

Alexander technique for chronic asthma

Breathing exercises for adults with asthma

Breathing exercises for children with asthma

Weight loss interventions for chronic asthma

Inspiratory muscle training for asthma

Water-based exercise for adults with asthma

Manual therapy for asthma

Physical training for asthma

Swimming training for asthma in children and adolescents aged 18 years and under

Yoga for asthma

Pulmonary rehabilitation (1)

Telerehabilitation for chronic respiratory disease (protocol stage)

Asthma, occupational (1)

Workplace interventions for treatment of occupational asthma

Asthma, primary prevention (3)

Interventions for autumn exacerbations of asthma in children

Interventions to improve adherence to inhaled steroids for asthma

Interventions to improve inhaler technique for people with asthma

Breathing dysregulation/hyperventilation syndrome (2)

Breathing exercises for dysfunctional breathing/hyperventilation syndrome in adults

Breathing exercises for dysfunctional breathing/hyperventilation syndrome in children

Bronchiectasis (46)

Anti inflammatory agents, non-steroidal (3)

Inhaled non-steroid anti-inflammatories for children and adults with bronchiectasis

Interventions for bronchiectasis: an overview of Cochrane systematic reviews

Oral non steroid anti-inflammatories for children and adults with bronchiectasis

Anti-bacterial agents (9)

Continuous versus intermittent antibiotics for bronchiectasis

Dual antibiotics for bronchiectasis

Head-to-head trials of antibiotics for bronchiectasis

Intermittent prophylactic antibiotics for bronchiectasis (protocol stage)

Interventions for bronchiectasis: an overview of Cochrane systematic reviews

Macrolide antibiotics for bronchiectasis

Oral versus inhaled antibiotics for bronchiectasis

Prolonged antibiotics for non-cystic fibrosis bronchiectasis in children and adults

Short courses of antibiotics for children and adults with bronchiectasis

Anticholinergics (2)

Interventions for bronchiectasis: an overview of Cochrane systematic reviews

Anticholinergic therapy for bronchiectasis

Beta-agonists (4)

Combination inhaled corticosteroids and long-acting beta-agonists for children and adults with bronchiectasis

Interventions for bronchiectasis: an overview of Cochrane systematic reviews

Long-acting beta2-agonists for bronchiectasis

Short acting beta2-agonists for bronchiectasis

Delivery of care (4)

Interventions for enhancing adherence to treatment in adults with bronchiectasis

Interventions for bronchiectasis: an overview of Cochrane systematic reviews

Nurse-led versus doctor-led care for bronchiectasis

Self-management for bronchiectasis

Environment exposure reduction (1)

Individual-level interventions to reduce personal exposure to outdoor air pollution and their effects on long-term respiratory conditions (protocol stage)

Leukotriene antagonists (2)

Interventions for bronchiectasis: an overview of Cochrane systematic reviews

Leukotriene receptor antagonists for non-cystic fibrosis bronchiectasis

Mucoactive agents (3)

Inhaled hyperosmolar agents for bronchiectasis

Interventions for bronchiectasis: an overview of Cochrane systematic reviews

Mucolytics for bronchiectasis

Physical therapy (6)

Airway clearance techniques for bronchiectasis

Exercise training for bronchiectasis (protocol stage)

Interventions for bronchiectasis: an overview of Cochrane systematic reviews

Positive expiratory pressure therapy versus other airway clearance techniques for bronchiectasis

Physical training for bronchiectasis

Singing for children and adults with bronchiectasis

Pulmonary rehabilitation (1)

Telerehabilitation for chronic respiratory disease (protocol stage)

Combination inhaled corticosteroids and long-acting beta-agonists for children and adults with bronchiectasis

Interventions for bronchiectasis: an overview of Cochrane systematic reviews

Oral corticosteroids for bronchiectasis (stable and acute exacerbations)

Inhaled corticosteroids for bronchiectasis

Interventions for bronchiectasis: an overview of Cochrane systematic reviews

Surgery versus non-surgical treatment for bronchiectasis

Influenza vaccine for children and adults with bronchiectasis

Interventions for bronchiectasis: an overview of Cochrane systematic reviews

Pneumococcal vaccines for children and adults with bronchiectasis

Interventions for bronchiectasis: an overview of Cochrane systematic reviews

Oral methylxanthines for bronchiectasis

Bronchoconstriction, exercise-induced (7)

Beta-agonists for exercise-induced asthma

Inhaled corticosteroids compared to placebo for prevention of exercise induced bronchoconstriction

Mast-cell stabilising agents to prevent exercise-induced bronchoconstriction

Nedocromil sodium for preventing exercise-induced bronchoconstriction

Nedocromil sodium versus sodium cromoglycate for preventing exercise-induced bronchoconstriction

Vitamin C for asthma and exercise-induced bronchoconstriction

Vitamins C and E for asthma and exercise-induced bronchoconstriction

Chronic obstructive pulmonary disease, stable - pharmacotherapy (103)

Adverse effects of treatments (1)

Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease

Antibodies, monoclonal (1)

Anti-IL5 therapies for chronic obstructive pulmonary disease (protocol stage)

Immunostimulants (1)

Immunostimulants versus placebo for preventing exacerbations in adults with chronic bronchitis or chronic obstructive pulmonary disease (protocol stage)

Muscarinic antagonists (19)

Combined aclidinium bromide and long-acting beta2-agonist for chronic obstructive pulmonary disease (COPD)

Umeclidinium bromide versus placebo for people with chronic obstructive pulmonary disease (COPD)

Combination inhaled steroid and long-acting beta-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease

Combination inhaled steroid and long-acting beta2-agonist versus tiotropium for chronic obstructive pulmonary disease

Aclidinium bromide for stable chronic obstructive pulmonary disease

Long-acting beta-agonist in addition to tiotropium versus either tiotropium or long-acting beta-agonist alone for chronic obstructive pulmonary disease

Glycopyrronium bromide for chronic obstructive pulmonary disease (protocol stage)

Ipratropium bromide versus long-acting beta-2 agonists for stable chronic obstructive pulmonary disease

Ipratropium bromide versus short acting beta-2 agonists for stable chronic obstructive pulmonary disease

Once-daily long-acting beta₂-agonists/inhaled corticosteroids combined inhalers versus inhaled long-acting muscarinic antagonists for people with chronic obstructive pulmonary disease

Once daily long-acting beta2-agonists and long-acting muscarinic antagonists in a combined inhaler versus placebo for chronic obstructive pulmonary disease

Pressurised metered-dose inhalers versus all other hand-held inhalers devices to deliver bronchodilators for chronic obstructive pulmonary disease

The effect of adding inhaled corticosteroids to tiotropium and long-acting beta₂-agonists for chronic obstructive pulmonary disease

Tiotropium versus placebo for chronic obstructive pulmonary disease

Tiotropium for stable chronic obstructive pulmonary disease

Tiotropium versus ipratropium bromide for chronic obstructive pulmonary disease

Tiotropium versus long-acting beta-agonists for stable chronic obstructive pulmonary disease

Long-acting muscarinic antagonist (LAMA) plus long-acting beta-agonist (LABA) versus LABA plus inhaled corticosteroid (ICS) for stable chronic obstructive pulmonary disease (COPD)

Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis

Beta-agonists, long-acting, twice daily (22)

Combined aclidinium bromide and long-acting beta2-agonist for chronic obstructive pulmonary disease (COPD)

Combination inhaled steroid and long-acting beta-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease

Bronchodilators delivered by nebuliser versus pMDI with spacer or DPI for exacerbations of COPD

Combined corticosteroid and long-acting beta-agonist in one inhaler versus inhaled corticosteroids alone for chronic obstructive pulmonary disease

Combination inhaled steroid and long-acting beta2-agonist versus tiotropium for chronic obstructive pulmonary disease

Inhaled corticosteroids versus long-acting beta-agonists for chronic obstructive pulmonary disease

Combined corticosteroid and long-acting beta₂-agonist in one inhaler versus long-acting beta₂-agonists for chronic obstructive pulmonary disease

Aclidinium bromide for stable chronic obstructive pulmonary disease

Long-acting beta-agonist in addition to tiotropium versus either tiotropium or long-acting beta-agonist alone for chronic obstructive pulmonary disease

Inhaled corticosteroids with combination inhaled long-acting beta-agonists and long-acting muscarinic antagonists for chronic obstructive pulmonary disease

Indacaterol, a once-daily beta-agonist, versus twice-daily beta-agonists or placebo for chronic obstructive pulmonary disease

Ipratropium bromide versus long-acting beta-2 agonists for stable chronic obstructive pulmonary disease

Once-daily long-acting beta₂-agonists/inhaled corticosteroids combined inhalers versus inhaled long-acting muscarinic antagonists for people with chronic obstructive pulmonary disease

Long-acting beta-agonists for chronic obstructive pulmonary disease

Long-acting beta2-agonists for poorly reversible chronic obstructive pulmonary disease

Once-daily LABA/ICS combined inhalers versus inhaled long-acting beta2-agonists for people with chronic obstructive pulmonary disease (COPD) (protocol stage)

Pressurised metered-dose inhalers versus all other hand-held inhalers devices to deliver bronchodilators for chronic obstructive pulmonary disease

The effect of adding inhaled corticosteroids to tiotropium and long-acting beta₂-agonists for chronic obstructive pulmonary disease

Tiotropium versus long-acting beta-agonists for stable chronic obstructive pulmonary disease

Long-acting muscarinic antagonist (LAMA) plus long-acting beta-agonist (LABA) versus LABA plus inhaled corticosteroid (ICS) for stable chronic obstructive pulmonary disease (COPD)

Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis

Dual combination therapy versus long-acting bronchodilators alone for chronic obstructive pulmonary disease (COPD): a systematic review and network meta-analysis

Beta-agonists, short-acting (4)

Bronchodilators delivered by nebuliser versus pMDI with spacer or DPI for exacerbations of COPD

Ipratropium bromide versus short acting beta-2 agonists for stable chronic obstructive pulmonary disease

Pressurised metered-dose inhalers versus all other hand-held inhalers devices to deliver bronchodilators for chronic obstructive pulmonary disease

Short-acting beta2-agonists for stable chronic obstructive pulmonary disease

Beta-agonists, long-acting, once daily (6)

Bronchodilators delivered by nebuliser versus pMDI with spacer or DPI for exacerbations of COPD

Indacaterol, a once-daily beta-agonist, versus twice-daily beta-agonists or placebo for chronic obstructive pulmonary disease

Once daily long-acting beta2-agonists and long-acting muscarinic antagonists in a combined inhaler versus placebo for chronic obstructive pulmonary disease

Long-acting muscarinic antagonist (LAMA) plus long-acting beta-agonist (LABA) versus LABA plus inhaled corticosteroid (ICS) for stable chronic obstructive pulmonary disease (COPD)

Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis

Dual combination therapy versus long-acting bronchodilators alone for chronic obstructive pulmonary disease (COPD): a systematic review and network meta-analysis

Proton pump inhibitors (1)

Proton pump inhibitors for chronic obstructive pulmonary disease (protocol stage)

Sexual dysfunction (1)

Interventions for sexual dysfunction in people with chronic obstructive pulmonary disease (COPD)

Statins versus placebo for people with chronic obstructive pulmonary disease

Steroids, inhaled (16)

Combination inhaled steroid and long-acting beta-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease

Combined corticosteroid and long-acting beta-agonist in one inhaler versus inhaled corticosteroids alone for chronic obstructive pulmonary disease

Combination inhaled steroid and long-acting beta2-agonist versus tiotropium for chronic obstructive pulmonary disease

Combined corticosteroid and long-acting beta-agonist in one inhaler versus placebo for chronic obstructive pulmonary disease

Inhaled corticosteroids versus long-acting beta-agonists for chronic obstructive pulmonary disease

Combined corticosteroid and long-acting beta₂-agonist in one inhaler versus long-acting beta₂-agonists for chronic obstructive pulmonary disease

Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease

Inhaled corticosteroids with combination inhaled long-acting beta-agonists and long-acting muscarinic antagonists for chronic obstructive pulmonary disease

Inhaled corticosteroid effects on bone metabolism in asthma and mild chronic obstructive pulmonary disease

Inhaled corticosteroids for stable chronic obstructive pulmonary disease

Once-daily long-acting beta₂-agonists/inhaled corticosteroids combined inhalers versus inhaled long-acting muscarinic antagonists for people with chronic obstructive pulmonary disease

Once-daily LABA/ICS combined inhalers versus inhaled long-acting beta2-agonists for people with chronic obstructive pulmonary disease (COPD) (protocol stage)

The effect of adding inhaled corticosteroids to tiotropium and long-acting beta₂-agonists for chronic obstructive pulmonary disease

Beclometasone for chronic obstructive pulmonary disease

Long-acting muscarinic antagonist (LAMA) plus long-acting beta-agonist (LABA) versus LABA plus inhaled corticosteroid (ICS) for stable chronic obstructive pulmonary disease (COPD)

Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis

Steroids, oral (1)

Oral corticosteroids for stable chronic obstructive pulmonary disease

Combination and additive therapies (15)

Combination inhaled steroid and long-acting beta-agonist in addition to tiotropium versus tiotropium or combination alone for chronic obstructive pulmonary disease

Combined corticosteroid and long-acting beta-agonist in one inhaler versus inhaled corticosteroids alone for chronic obstructive pulmonary disease

Combination inhaled steroid and long-acting beta2-agonist versus tiotropium for chronic obstructive pulmonary disease

Combined corticosteroid and long-acting beta-agonist in one inhaler versus placebo for chronic obstructive pulmonary disease

Combined corticosteroid and long-acting beta₂-agonist in one inhaler versus long-acting beta₂-agonists for chronic obstructive pulmonary disease

Long-acting beta-agonist in addition to tiotropium versus either tiotropium or long-acting beta-agonist alone for chronic obstructive pulmonary disease

Inhaled corticosteroids with combination inhaled long-acting beta-agonists and long-acting muscarinic antagonists for chronic obstructive pulmonary disease

Ipratropium bromide versus long-acting beta-2 agonists for stable chronic obstructive pulmonary disease

Ipratropium bromide versus short acting beta-2 agonists for stable chronic obstructive pulmonary disease

Once-daily long-acting beta₂-agonists/inhaled corticosteroids combined inhalers versus inhaled long-acting muscarinic antagonists for people with chronic obstructive pulmonary disease

Once daily long-acting beta2-agonists and long-acting muscarinic antagonists in a combined inhaler versus placebo for chronic obstructive pulmonary disease

Once-daily LABA/ICS combined inhalers versus inhaled long-acting beta2-agonists for people with chronic obstructive pulmonary disease (COPD) (protocol stage)

The effect of adding inhaled corticosteroids to tiotropium and long-acting beta₂-agonists for chronic obstructive pulmonary disease

Long-acting inhaled therapy (beta-agonists, anticholinergics and steroids) for COPD: a network meta-analysis

Dual combination therapy versus long-acting bronchodilators alone for chronic obstructive pulmonary disease (COPD): a systematic review and network meta-analysis

Cardioselective beta-blockers (1)

Cardioselective beta-blockers for chronic obstructive pulmonary disease

Mucolytic agents (1)

Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease

Phosphodiesterases (1)

Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary disease

Anti-bacterial agents (4)

Antibiotics for exacerbations of chronic obstructive pulmonary disease

Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD)

Head-to-head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease

Prophylactic antibiotics for adults with chronic obstructive pulmonary disease: a network meta-analysis (protocol stage)

Pneumococcal vaccines for preventing pneumonia in chronic obstructive pulmonary disease

Influenza vaccine for chronic obstructive pulmonary disease (COPD)

Delivery of inhaled therapy (2)

Bronchodilators delivered by nebuliser versus pMDI with spacer or DPI for exacerbations of COPD

Pressurised metered-dose inhalers versus all other hand-held inhalers devices to deliver bronchodilators for chronic obstructive pulmonary disease

Methylxanthines for exacerbations of chronic obstructive pulmonary disease

Oral theophylline for chronic obstructive pulmonary disease

Oral xanthine derivatives (theophylline and doxofylline) for patients with stable chronic obstructive pulmonary disease (COPD) (protocol stage)

Chronic obstructive pulmonary disease, stable - non-pharmacotherapy (61)

Complementary therapies (4)

Active mind-body movement therapies as an adjunct to or in comparison with pulmonary rehabilitation for people with chronic obstructive pulmonary disease

Acupuncture point stimulation for chronic obstructive pulmonary disease (protocol stage)

Upper limb exercise training for COPD

Tai Chi for chronic obstructive pulmonary disease (COPD)

Delivery of care (10)

Digital interventions for the management of chronic obstructive pulmonary disease (protocol stage)

Home care by outreach nursing for chronic obstructive pulmonary disease

Integrated disease management interventions for patients with chronic obstructive pulmonary disease

Interventions for promoting physical activity in people with COPD (protocol stage)

Interventions to promote referral, uptake and adherence to pulmonary rehabilitation for people with chronic obstructive pulmonary disease (COPD) (protocol stage)

Pulmonary rehabilitation for chronic obstructive pulmonary disease

Pulmonary rehabilitation using minimal equipment for people with chronic obstructive pulmonary disease (COPD) (protocol stage)

Targeted interventions and approaches to care for people living with chronic obstructive pulmonary disease and at least one other long-term condition: a mixed methods review (protocol stage)

Telehealthcare for remote monitoring and consultations for people with chronic obstructive pulmonary disease (COPD) (protocol stage)

Telerehabilitation for chronic respiratory disease (protocol stage)

Diet therapy and nutritional support (2)

Nutritional supplementation for stable chronic obstructive pulmonary disease

Vitamin D for the management of chronic obstructive pulmonary disease (protocol stage)

Education and disease management (10)

Digital interventions for the management of chronic obstructive pulmonary disease (protocol stage)

Educational interventions for health professionals managing COPD in primary care (protocol stage)

Integrated disease management interventions for patients with chronic obstructive pulmonary disease

Interventions to improve adherence to pharmacological therapy for chronic obstructive pulmonary disease (COPD) (protocol stage)

Non-pharmacological management interventions for COPD: an overview of Cochrane systematic reviews (protocol stage)

Self management for patients with chronic obstructive pulmonary disease

Self-management interventions including action plans for exacerbations versus usual care in patients with chronic obstructive pulmonary disease

Computer and mobile technology interventions for self-management in chronic obstructive pulmonary disease

Telehealthcare for chronic obstructive pulmonary disease

Telehealthcare for remote monitoring and consultations for people with chronic obstructive pulmonary disease (COPD) (protocol stage)

Environment exposure reduction (1)

Individual-level interventions to reduce personal exposure to outdoor air pollution and their effects on long-term respiratory conditions (protocol stage)

Oxygen therapy and ventilation (7)

Non-invasive ventilation during exercise training for people with chronic obstructive pulmonary disease

Domiciliary oxygen for chronic obstructive pulmonary disease

Nocturnal non-invasive positive pressure ventilation for stable chronic obstructive pulmonary disease

Oxygen therapy during exercise training in chronic obstructive pulmonary disease

Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen therapy

Ambulatory oxygen for people with chronic obstructive pulmonary disease who are not hypoxaemic at rest

Short-term ambulatory oxygen for chronic obstructive pulmonary disease

Palliative care (0)

Physical therapy (16)

Active mind-body movement therapies as an adjunct to or in comparison with pulmonary rehabilitation for people with chronic obstructive pulmonary disease

Acupuncture point stimulation for chronic obstructive pulmonary disease (protocol stage)

Airway clearance techniques for chronic obstructive pulmonary disease

Upper limb exercise training for COPD

Breathing exercises for chronic obstructive pulmonary disease

Non-invasive ventilation during exercise training for people with chronic obstructive pulmonary disease

Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease

Interventions for promoting physical activity in people with COPD (protocol stage)

Interventions to promote referral, uptake and adherence to pulmonary rehabilitation for people with chronic obstructive pulmonary disease (COPD) (protocol stage)

Neuromuscular electrostimulation for adults with chronic obstructive pulmonary disease

Oxygen therapy during exercise training in chronic obstructive pulmonary disease

Pulmonary rehabilitation for chronic obstructive pulmonary disease

Pulmonary rehabilitation using minimal equipment for people with chronic obstructive pulmonary disease (COPD) (protocol stage)

Tai Chi for chronic obstructive pulmonary disease (COPD)

Unsupervised exercise training versus no exercise training for chronic obstructive pulmonary disease (protocol stage)

Water-based exercise training for chronic obstructive pulmonary disease

Psychotherapy (0)

Pulmonary rehabilitation (6)

Factors influencing referral to and uptake and attendance of pulmonary rehabilitation for chronic obstructive pulmonary disease: a qualitative evidence synthesis of the experiences of service users, their families, and healthcare providers (protocol stage)

Interventions to promote referral, uptake and adherence to pulmonary rehabilitation for people with chronic obstructive pulmonary disease (COPD) (protocol stage)

Pulmonary rehabilitation for chronic obstructive pulmonary disease

Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease

Pulmonary rehabilitation using minimal equipment for people with chronic obstructive pulmonary disease (COPD) (protocol stage)

Telerehabilitation for chronic respiratory disease (protocol stage)

Sexual dysfunction (1)

Interventions for sexual dysfunction in people with chronic obstructive pulmonary disease (COPD)

Smoking cessation (2)

Smoking cessation for chronic obstructive pulmonary disease

Smoking cessation for people with chronic obstructive pulmonary disease

Bronchoscopic lung volume reduction procedures for chronic obstructive pulmonary disease

Lung volume reduction surgery for diffuse emphysema

Chronic obstructive pulmonary disease, exacerbations (24)

Anti-bacterial agents (1)

Biomarkers to guide antibiotic therapy for COPD exacerbations (protocol stage)

Anticholinergics (3)

Anticholinergic bronchodilators versus beta2-sympathomimetic agents for acute exacerbations of chronic obstructive pulmonary disease

Bronchodilators delivered by nebuliser versus pMDI with spacer or DPI for exacerbations of COPD

Inhaled short-acting beta2-agonists versus ipratropium for acute exacerbations of chronic obstructive pulmonary disease

Beta-agonists (4)

Anticholinergic bronchodilators versus beta2-sympathomimetic agents for acute exacerbations of chronic obstructive pulmonary disease

Bronchodilators delivered by nebuliser versus pMDI with spacer or DPI for exacerbations of COPD

Inhaled short-acting beta2-agonists versus ipratropium for acute exacerbations of chronic obstructive pulmonary disease

Methylxanthines for exacerbations of chronic obstructive pulmonary disease

Biomarkers to guide antibiotic therapy for COPD exacerbations (protocol stage)

Education and disease management (2)

Action plans with brief patient education for exacerbations in chronic obstructive pulmonary disease

Self-management interventions including action plans for exacerbations versus usual care in patients with chronic obstructive pulmonary disease

Magnesium sulfate (0)

Different durations of corticosteroid therapy for exacerbations of chronic obstructive pulmonary disease

Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease

Pulmonary rehabilitation (2)

Interventions to promote referral, uptake and adherence to pulmonary rehabilitation for people with chronic obstructive pulmonary disease (COPD) (protocol stage)

Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease

Oxygen therapy and ventilation (3)

Heliox for treatment of exacerbations of chronic obstructive pulmonary disease

Non-invasive ventilation for the management of acute hypercapnic respiratory failure due to exacerbation of chronic obstructive pulmonary disease

Oxygen therapy in the pre-hospital setting for acute exacerbations of chronic obstructive pulmonary disease

Delivery of care (2)

Hospital at home for acute exacerbations of chronic obstructive pulmonary disease

Interventions to promote referral, uptake and adherence to pulmonary rehabilitation for people with chronic obstructive pulmonary disease (COPD) (protocol stage)

Antibiotics for exacerbations of chronic obstructive pulmonary disease

Carbonic anhydrase inhibitors for hypercapnic ventilatory failure in chronic obstructive pulmonary disease

Doxapram for ventilatory failure due to exacerbations of chronic obstructive pulmonary disease

Singing for adults with chronic obstructive pulmonary disease

Cough, chronic (18)

Anti-bacterial agents (2)

Antibiotics for persistent cough or wheeze following acute bronchiolitis in children

Antibiotics for prolonged wet cough in children

Anticholinergics (1)

Anticholinergics for prolonged non-specific cough in children

Antihistamines (1)

Anti-histamines for prolonged non-specific cough in children

Beta-agonists (1)

Inhaled beta2-agonists for non-specific chronic cough in children

Inhaled cromones for prolonged non-specific cough in children

Delivery of care (1)

Clinical pathways for chronic cough in children

Environmental remediation and allergen reduction (1)

Indoor air modification interventions for prolonged non-specific cough in children

Gastro-oesophageal reflux treatment (1)

Gastro-oesophageal reflux treatment for prolonged non-specific cough in children and adults

Leukotriene antagonists (1)

Leukotriene receptor antagonist for prolonged non-specific cough in children

Speech and language therapy (1)

Speech and language therapy for management of chronic cough

Inhaled corticosteroids for subacute and chronic cough in adults

Inhaled corticosteroids for subacute cough in children

Inhaled corticosteroids for non-specific chronic cough in children

Topical treatment (2)

Codeine versus placebo for chronic cough in children

Honey and lozenges for children with non-specific cough

Treatment of sleep apnea (1)

Treatment of obstructive sleep apnoea for chronic cough in children

Methylxanthines for prolonged non-specific cough in children

Cough, post-viral (1)

Antibiotics for persistent cough or wheeze following acute bronchiolitis in children

Cough, subacute (2)

Inhaled corticosteroids for subacute and chronic cough in adults

Inhaled corticosteroids for subacute cough in children

Diagnostic test accuracy (1)

Galactomannan detection for invasive aspergillosis in immunocompromised patients

Global developmental delay (1)

Non-pharmaceutical management of respiratory morbidity in children with severe global developmental delay

Hypertension, pulmonary (10)

Anticoagulation therapy versus placebo for pulmonary hypertension

Calcium channel blockers for pulmonary arterial hypertension

Doppler trans-thoracic echocardiography for detection of pulmonary hypertension in adults (protocol stage)

Endothelin receptor antagonists for pulmonary arterial hypertension

Exercise-based rehabilitation programmes for pulmonary hypertension

Phosphodiesterase 5 inhibitors for pulmonary hypertension

Phosphodiesterase 5 inhibitors for pulmonary hypertension

Prostacyclin for pulmonary hypertension in adults

Prostacyclin for pulmonary arterial hypertension

Guanylate cyclase stimulators for pulmonary hypertension

Idiopathic pulmonary fibrosis (4)

Corticosteroids for idiopathic pulmonary fibrosis

Non-steroid agents for idiopathic pulmonary fibrosis

Prognosis of adults with idiopathic pulmonary fibrosis without treatment or without effective therapies (protocol stage)

Telerehabilitation for chronic respiratory disease (protocol stage)

Lung disease, aspiration (1)

Restriction of oral intake of water for aspiration lung disease in children

Lung diseases, interstitial (6)

Cyclophosphamide for connective tissue disease–associated interstitial lung disease

Domiciliary oxygen for interstitial lung disease

Nebulised morphine for severe interstitial lung disease

Pulmonary rehabilitation for interstitial lung disease

Telerehabilitation for chronic respiratory disease (protocol stage)

Ambulatory and short-burst oxygen for interstitial lung disease

Obesity hypoventilation syndrome (1)

Non-invasive positive airway pressure therapy for obesity hypoventilation syndrome in adults (protocol stage)

Pleural diseases (1)

Intra-pleural fibrinolytic therapy versus conservative management in the treatment of adult parapneumonic effusions and empyema

Sarcoidosis, pulmonary (2)

Corticosteroids for pulmonary sarcoidosis

Immunosuppressive and cytotoxic therapy for pulmonary sarcoidosis

Sleep apnoea, central (2)

Non-invasive positive pressure ventilation for central sleep apnoea in adults (protocol stage)

Pharmacological treatment for central sleep apnoea in adults (protocol stage)

Sleep apnoea, obstructive (21)

Continuous positive airways pressure (7)

Continuous positive airway pressure delivery interfaces for obstructive sleep apnoea

Continuous positive airways pressure for obstructive sleep apnoea in adults

Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea

Non-invasive positive airway pressure therapy for improving erectile dysfunction in men with obstructive sleep apnoea (protocol stage)

Non-invasive positive airway pressure therapy for obesity hypoventilation syndrome in adults (protocol stage)

Oral appliances for obstructive sleep apnoea (protocol stage)

Pressure modification for improving usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea

Oral appliance therapy (2)

Oral appliances for obstructive sleep apnoea (protocol stage)

Oral appliances for obstructive sleep apnoea

Drug treatment (3)

Anti-inflammatory medications for obstructive sleep apnea in children

Drug therapy for obstructive sleep apnoea in adults

Effects of opioid, hypnotic and sedating medications on sleep-disordered breathing in adults with obstructive sleep apnoea

Lifestyle modification (2)

Positional therapy for obstructive sleep apnoea

Lifestyle modification for obstructive sleep apnoea

Physical therapy (2)

Positional therapy for obstructive sleep apnoea

Myofunctional therapy (oropharyngeal exercises) for obstructive sleep apnoea (protocol stage)

Oral appliances for obstructive sleep apnoea (protocol stage)

Surgery for obstructive sleep apnoea in adults (protocol stage)

Surgery for obstructive sleep apnoea in adults

Tonsillectomy versus tonsillotomy for sleep-disordered breathing in children (protocol stage)

Tonsillectomy or adenotonsillectomy versus non-surgical management for obstructive sleep-disordered breathing in children

Stridor, post-extubation (1)

Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults

Tracheomalacia (1)

Interventions for primary (intrinsic) tracheomalacia in children

Anticholinergic drugs for wheeze in children under the age of two years

Inhaled steroids for episodic viral wheeze of childhood

Ketotifen alone or as additional medication for long-term control of asthma and wheeze in children

Parent-initiated oral corticosteroid therapy for intermittent wheezing illnesses in children

Short acting beta2-agonists for recurrent wheeze in children under two years of age

Systemic steroids versus placebo for acute wheeze in preschool aged children (protocol stage)

Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children

New and Updated (in the latest issue of the CLib):

New

Anti-IL5 therapies for chronic obstructive pulmonary disease

New

Individual-level interventions to reduce personal exposure to outdoor air pollution and their effects on long-term respiratory conditions

New

Myofunctional therapy (oropharyngeal exercises) for obstructive sleep apnoea

New

Psychological interventions for asthma in children and adolescents

Updated

Inhaled steroids with and without regular formoterol for asthma: serious adverse events

Updated

Workplace interventions for treatment of occupational asthma